Does Plaquenil Cause Darkening Of The Skin?

The abnormal amount of cortisol in the human body causes a. These are cells that produce pigmentation in the skin.

Yellow Skin Discoloration Induced By Quinacrine In A Patient With Cutaneous Lupus Erythematosus Actas Dermo Sifiliograficas

The plaquenil made me lose my hair immediately.

Does plaquenil cause darkening of the skin?. 21052010 I was diagnosed almost 2yrs ago with Lupus SLE. April 21 2009 081015 PM. 10012021 Darkened skin or hyperpigmentation is not typically a symptom of a life-threatening condition nor does it on its own lead to complications.

However prolonged use of topical hydroquinone without any breaks in use can cause darkening of the skin known as ochronosis. 05022020 Skin darkening is common among people and Hyperpigmentation is the term used to denote over- blackening of skin. Blistering peeling loosening of the skin.

Melanin is the substance that provides color to the skin and protects it from the sun. However trauma and bruising may faciliate the developement of pigmentation. If experienced these tend to have a Less Severe expression i.

Common causes include but are not limited to acne eczema pseudofolliculitis barbae razor bumps atopic or allergic contact dermatitis insect bites skin exposure to topical irritants trauma psoriasis. It is important to evaluate this color change to make sure there is nothing else wrong. 09012021 Serious skin reactions including Stevens-Johnson syndrome toxic epidermal necrolysis drug reaction with eosinophilia and systemic symptoms DRESS and acute generalized exanthematous pustulosis can occur during treatment with this medicine.

The exact reasons why this phenomenon happens is not clear. Even if you are using brightening skin care products or undergoing laser treatments for pigmentation if you are taking this supplement you may still notice skin darkening. 23112010 Apart from too much exposure to the sun medical conditions like Addisons disease melasma and lupus can cause darkening of the skin.

However a few people may develop one of the following. Melanin producing cells also known as melanocytes lie in the lowest layer of the epidermis. As a result there is both hemosiderin iron and melanin accumulation in the dermis.

30092019 This medication usually contains hydroquinone which lightens the skin. 29012019 Darkened armpits are often a result of post-inflammatory hyperpigmentation PIH a darkening of the skin that occurs after there is damage or irritation to the skin. You might also experience darkening anywhere where your skin folds a lot like your elbows knees underarms and.

Hydroxychloroquine Plaquenil stimulates the pigment producing cells in the skin called melanocytes. Skin darkening commonly referred to as hyperpigmentation is an indication that too much melanin pigment is being produced in the skin. Blurred vision or other vision changes.

Rash indigestion diarrhoea headache blurred vision cramps or muscle weakness darkening of the skin or bleaching of the hair. 11022021 Usually this shows up as sun spots or freckles. Melatonin activates Melanocytes so by taking this supplement you are potentially susceptible to hyper-pigmentation.

When there is excessive production of melanin it can lead to formation of small dark patches on the skin. Discoloration of the mouth. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine.

Plaquenil and skin discoloration. It is also the cause of darkened spots on skin but which is a harmless skin condition where the skin becomes darker than usual. Hydroxychloroquine can aggravate pre-existing psoriasis.

When it came back in most of it came in white which I read that the medicine can bleach your hair. 03062018 Why does it occur. However certain disorders associated with hyperpigmentation can lead to complications that are life threatening.

07052020 Although not all of these side effects may occur if they do occur they may need medical attention. Then last year I noticed areas on my legs that are brown or maybe its that my skin has been bleached in areas and is very white. Hyper-pigmentation is a possible side effect of chloroquine medications chloroquine binds with melanin causing patchy or mottled spots on areas of skin exposed to sunlight.

Discolored skin patches also commonly develop in a particular part of the body due to a change in melanin levels. Skin can darken when there is an overproduction of melanin. Side effects are uncommon.

15122017 The disease causes darkening of the skin in certain areas. The spots can range in colors from blueish to brown in color. Skin darkening can develop in people of all races and ethnicities.

18082011 Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin andor mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber.

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